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ศูนย์โอมิกส์แห่งชาติ
ศูนย์โอมิกส์แห่งชาติ
Metabolomics
Metabolomics is a new member of omics and aims to annotate and comprehensively characterize metabolites including small molecules in biological samples. These putative compounds are required for a cascade of sequential steps for a research question. Strategic workflow starts with experimental design, sample preparation, mass analysis, data and statistical analysis, pathway analysis, and hypothesis generation. Separation and measurement of extracted metabolites can be performed by using chromatographic techniques (Liquid chromatography, LC). Annotation and characterization are performed using spectroscopic (nuclear magnetic resonance, NMR) or spectrometric (Mass spectrometry, MS) methods.
Characterization & annotation of metabolites and small molecules:
Mass spectrometry-based analysis can be used to generate chemical profiling, volatile compound fingerprints and broaden your investigation with metabolome comparison. Highlight the application in food industry, pharmaceuticals, medicine, cosmetics and agriculture.
Trace quantitative analysis: LCMS can quantify targeted compounds and also measure trace
contaminants and residue of metabolites, drug and pesticides in your samples.
High- throughput cellular imaging:
Microscopy platform helps you to visualize and understand cellular mechanism of your fixed and living cells. High content screening (HCS) allows you to explore the effects of compounds in complex cellular systems such as cells, organoid and spheroid via image analysis and quantify your data to meet new dimension of knowledge.