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Distribution of hsp65 PCR-restriction enzyme analysis patterns among mycobacterium avium complex isolates in Thailand
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Document Title
Distribution of hsp65 PCR-restriction enzyme analysis patterns among mycobacterium avium complex isolates in Thailand
Author
Prammananan T, Phunpruch S, Tingtoy N, Srimuang S, Chaiprasert A
Name from Authors Collection
Affiliations
Mahidol University; Mahidol University; National Science & Technology Development Agency - Thailand; National Center Genetic Engineering & Biotechnology (BIOTEC); King Mongkuts Institute of Technology Ladkrabang
Type
Article
Source Title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN
0095-1137
Year
2006
Volume
44
Issue
10
Page
3819-3821
Open Access
Green Published
Publisher
AMER SOC MICROBIOLOGY
DOI
10.1128/JCM.02495-05
Format
Abstract
A total of 227 clinical Mycobacterium avium complex isolates from Thailand were differentiated into species and types by using PCR-restriction enzyme analysis of hsp65. The distribution of types showed the predominance of M. avium 1 (77%) in blood specimens, whereas M. intracellulare I was more commonly found in pulmonary specimens (44.2%). In addition, infections with M. avium were more likely to be found in younger adults (20 to 39 years old), while infections with M. intracellulare were more likely to be found in older adults (>= 60 years old). Our results provide the useful epidemiological information that some particular types have more invasive and virulent characters than others.
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WOS