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A facile one-pot green synthesis of gold nanoparticle-graphene-PEDOT: PSS nanocomposite for selective electrochemical detection of dopamine
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Document Title
A facile one-pot green synthesis of gold nanoparticle-graphene-PEDOT: PSS nanocomposite for selective electrochemical detection of dopamine
Author
Pananon P, Sriprachuabwong C, Wisitsoraat A, Chuysinuan P, Tuantranont A, Saparpakorn P, Dechtrirat D
Name from Authors Collection
Scopus Author ID
8532633300
Affiliations
Kasetsart University; National Science & Technology Development Agency - Thailand; National Electronics & Computer Technology Center (NECTEC); Chulabhorn Research Institute; Kasetsart University; Kasetsart University
Type
Article
Source Title
RSC ADVANCES
ISSN
2046-2069
Year
2018
Volume
8
Issue
23
Page
12724-12732
Open Access
Green Published, gold
Publisher
ROYAL SOC CHEMISTRY
DOI
10.1039/c8ra01564c
Format
Abstract
A facile one-pot and green method was developed to prepare a nanocomposite of gold nanoparticle (AuNP), graphene (GP) and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS). Graphene was first electro-exfoliated in a polystyrene sulfonate solution, followed by a one-step simultaneous in situ formation of gold nanoparticle and PEDOT. The as-synthesized aqueous dispersion of AuNP-GP-PEDOT:PSS was thereafter used to modify the glassy carbon electrode (GCE). For the first time, the quaternary composite between AuNP, GP, PEDOT and PSS was used for selective determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA). In comparison to a bare GCE, the nanocomposite electrode shows considerably higher electrocatalytic activities toward the oxidation of DA and UA due to a synergistic effect between AuNP, GP, PEDOT and PSS. Using differential pulse voltammetry (DPV), selective determination of DA and UA in the presence of AA could be achieved with a peak potential separation of 110mV between DA and UA. The sensor exhibits wide linear responses for DA and UA in the ranges of 1 nM to 300 M and 10 M to 1 mM with detection limits (S/N = 3) of 100 pM and 10 M, respectively. Furthermore, the proposed sensor was also successfully used to determine DA in a real pharmaceutical injection sample as well as DA and UA in human serum with satisfactory recovery results.
Industrial Classification
Knowledge Taxonomy Level 1
Knowledge Taxonomy Level 2
Funding Sponsor
Kasetsart University Research and Development Institute (KURDI); Development and Promotion of Science and Technology Talents Project (DPST); Institute for the Promotion of Teaching Science and Technology (IPST) [015/2558]; Graduate Program Scholarship from The Graduate School, Kasetsart University
License
CC BY-NC
Rights
Publisher
Publication Source
WOS