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Research Note Possible influence of thermal selection on patterns of HSP70 and HSP90 gene polymorphisms in Thai indigenous and local chicken breeds and red junglefowls
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Document Title
Research Note Possible influence of thermal selection on patterns of HSP70 and HSP90 gene polymorphisms in Thai indigenous and local chicken breeds and red junglefowls
Author
Budi T. Singchat W. Tanglertpaibul N. Thong T. Panthum T. Noito K. Wattanadilokchatkun P. Jehangir M. Chaiyes A. Wongloet W. Vangnai K. Yokthongwattana C. Sinthuvanich C. Ahmad S.F. Muangmai N. Han K. Nunome M. Supnithi T. Koga A. Duengkae P. Matsuda Y. Srikulnath K.
Affiliations
Animal Genomics and Bioresource Research Unit (AGB Research Unit) Faculty of Science Kasetsart University Bangkok Chatuchak 10900 Thailand; Interdisciplinary Graduate Program in Bioscience Faculty of Science Kasetsart University Bangkok Chatuchak 10900 Thailand; Special Research Unit for Wildlife Genomics (SRUWG) Department of Forest Biology Faculty of Forestry Kasetsart University Bangkok Chatuchak 10900 Thailand; School of Agriculture and Cooperatives Sukhothai Thammathirat Open University Nonthaburi 11120 Thailand; Department of Food Science and Technology Faculty of Agro-Industry Kasetsart University Bangkok 10900 Thailand; Department of Biochemistry Faculty of Science Kasetsart University Bangkok 10900 Thailand; Department of Fishery Biology Faculty of Fisheries Kasetsart University Bangkok 10900 Thailand; Department of Microbiology Dankook University Cheonan 31116 South Korea; Bio-Medical Engineering Core Facility Research Center Dankook University Cheonan 31116 South Korea; Smart Animal Bio institute Dankook University Cheonan 31116 South Korea; Department of Zoology Faculty of Science Okayama University of Science Okayama Kita-ku 700-0005 Japan; National Electronics and Computer Technology Center (NECTEC) Khlong Luang Thani Pathum 12120 Thailand; Center for Advanced Studies in Tropical Natural Resources National Research University-Kasetsart University (CASTNAR NRU-KU) Kasetsart University Bangkok 10900 Thailand
Type
Article
Source Title
Poultry Science
ISSN
325791
Year
2024
Volume
103
Issue
4
Open Access
All Open Access Gold
Publisher
Elsevier Inc.
DOI
10.1016/j.psj.2024.103503
Abstract
The thermal stress caused by global climate change adversely affects the welfare productivity and reproductive performance of farm animals including chickens and causes substantial economic losses. However the understanding of the genetic basis of the indigenous chicken adaptation to high ambient temperatures is limited. Hence to reveal the genetic basis of thermal stress adaptation in chickens this study investigated polymorphisms in the heat shock protein 70 (HSP70) and HSP90 genes known mechanisms of cellular defense against thermal stress in indigenous and local chicken breeds and red junglefowls in Thailand. The result revealed seven alleles of the HSP70 gene. One allele exhibited a missense mutation where an amino acid changed from Asn to His in the substrate-binding and peptide-binding domains which is exclusive to the Lao Pa Koi chicken breed. Twenty new alleles with silent mutations in the HSP90 gene highlighted its greater complexity. Despite this diversity distinct population structures were not found for either HSP70 or HSP90 which suggests incomplete impact on the domestication process and selection. The low genetic diversity shown by the sharing of alleles between red junglefowls and Thai indigenous and local chicken breeds aligns with the hypothesis that these alleles have undergone selection in tropical regions such as Thailand. Selection signature analysis suggests the purifying selection of HSP70 for thermotolerance. This study provides valuable insights for enhancing the conservation of genetic resources with thermotolerant traits which are essential for developing breeding programs to increase poultry production in the context of global climate change. ? 2024 The Authors
Keyword
allele | chicken breed | purifying selection | thermal stress | tropical
License
CC BY-NC-ND
Rights
Authors
Publication Source
WOS