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A facile one-pot green synthesis of gold nanoparticle-graphene-PEDOT:PSS nanocomposite for selective electrochemical detection of dopamine
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Metadata
Document Title
A facile one-pot green synthesis of gold nanoparticle-graphene-PEDOT:PSS nanocomposite for selective electrochemical detection of dopamine
Author
Pananon P., Sriprachuabwong C., Wisitsoraat A., Chuysinuan P., Tuantranont A., Saparpakorn P., Dechtrirat D.
Name from Authors Collection
Scopus Author ID
8532633300
Affiliations
Department of Materials Science, Faculty of Science, Kasetsart University, Bangkok, Thailand; National Electronics and Computer Technology Center (NECTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, Thailand; Laboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok, Thailand; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand; Specialized Center of Rubber and Polymer Materials for Agriculture and Industry (RPM), Faculty of Science, Kasetsart University, Bangkok, Thailand
Type
Article
Source Title
RSC Advances
ISSN
20462069
Year
2018
Volume
8
Issue
23
Page
12724-12732
Open Access
Gold, Green
Publisher
Royal Society of Chemistry
DOI
10.1039/c8ra01564c
Abstract
A facile one-pot and green method was developed to prepare a nanocomposite of gold nanoparticle (AuNP), graphene (GP) and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS). Graphene was first electro-exfoliated in a polystyrene sulfonate solution, followed by a one-step simultaneous in situ formation of gold nanoparticle and PEDOT. The as-synthesized aqueous dispersion of AuNP-GP-PEDOT:PSS was thereafter used to modify the glassy carbon electrode (GCE). For the first time, the quaternary composite between AuNP, GP, PEDOT and PSS was used for selective determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA). In comparison to a bare GCE, the nanocomposite electrode shows considerably higher electrocatalytic activities toward the oxidation of DA and UA due to a synergistic effect between AuNP, GP, PEDOT and PSS. Using differential pulse voltammetry (DPV), selective determination of DA and UA in the presence of AA could be achieved with a peak potential separation of 110 mV between DA and UA. The sensor exhibits wide linear responses for DA and UA in the ranges of 1 nM to 300 μM and 10 μM to 1 mM with detection limits (S/N = 3) of 100 pM and 10 μM, respectively. Furthermore, the proposed sensor was also successfully used to determine DA in a real pharmaceutical injection sample as well as DA and UA in human serum with satisfactory recovery results. © 2018 The Royal Society of Chemistry.
Industrial Classification
Knowledge Taxonomy Level 1
Knowledge Taxonomy Level 2
Knowledge Taxonomy Level 3
Funding Sponsor
Kasetsart University Research and Development Institute; Graduate School, Kasetsart University
License
CC BY-NC
Rights
Author
Publication Source
Scopus