-
Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. nov
- Back
Document Title
Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. nov
Author
Pathompong P, Pfutze S, Surup F, Boonpratuang T, Choeyklin R, Matasyoh JC, Decock C, Stadler M, Boonchird C
Name from Authors Collection
Affiliations
Mahidol University; German Center for Infection Research; Helmholtz Association; Helmholtz-Center for Infection Research; Braunschweig University of Technology; National Science & Technology Development Agency - Thailand; Egerton University
Type
Article
Source Title
MOLECULES
Year
2022
Volume
27
Issue
18
Open Access
Green Published, gold
Publisher
MDPI
DOI
10.3390/molecules27185968
Format
Abstract
Five new drimane-type sesquiterpenoids were isolated from cultures of the tropical basidiomycetes, Perenniporia centrali-africana (originating from Kenya) and Cerrena sp. nov. (originating from Thailand). A new pereniporin A derivative (1), a new drimane-type sesquiterpene lactam (2), and the new 6,7-Dehydro-isodrimenediol (3) were isolated from P. centrali-africana. In parallel, the two new drimane-type sesquiterpene lactams 5 and 6 were isolated together with known isodrimenediol (4) from Cerrena sp. This is the first report of drimane-type sesquiterpene lactams from basidiomycetes. The structures were elucidated based on 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data, in combination with high-resolution electrospray mass spectrometric (HR-ESIMS) data. The compounds were devoid of significant antimicrobial and cytotoxic activities.
Funding Sponsor
Royal Golden Jubilee Ph.D. Program (RGJ-PhD) [PHD/0039/2560]; German Academic Exchange Service (DAAD) [57507870]; ASAFEM Project under the ERAfrica Programme [IC-070]; European Union [101008129: MYCOBIOMICS]; Mahidol University; CIF Grant, Faculty of Science, Mahidol University
License
CC BY
Rights
Authors
Publication Source
WOS