Stanford University; National Science & Technology Development Agency - Thailand; National Electronics & Computer Technology Center (NECTEC); National Nanotechnology Center (NANOTEC); Stanford University; Stanford University; University of Michigan System; University of Michigan
Type
Article
Source Title
OPTICS EXPRESS
ISSN
1094-4087
Year
2008
Volume
16
Issue
10
Page
7224-7232
Open Access
Green Accepted, gold
Publisher
OPTICAL SOC AMER
DOI
10.1364/OE.16.007224
Format
PDF
Abstract
We present a handheld dual-axes confocal microscope that is based on a two-dimensional microelectromechanical systems (MEMS) scanner. It performs reflectance and fluorescence imaging at 488 nm wavelength, with three-dimensional imaging capability. The fully packaged microscope has a diameter of 10 mm and acquires images at 4 Hz frame rate with a maximum field of view of 400 mu m x 260 mu m. The transverse and axial resolutions of the handheld probe are 1.7 mu m and 5.8 mu m, respectively. Capability to perform real time small animal imaging is demonstrated in vivo in transgenic mice. (C) 2008 Optical Society of America.
